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The national strategy for biosurveillance calls for a coordinated approach for threats to public health and safety. This coordinated approach brings together federal, state and local governments, private sector, nongovernmental organizations and international partners to enhance existing biosurveillance capabilities and develop new ones that provide decision-makers and responders with the essential information to manage these threats. This strategy recognizes that a well-integrated national biosurveillance enterprise can saves lives by providing essential information for better decision making at all levels. This conference will address implementation strategies for the national strategy for biosurveillance identified core functions.

Final Agenda

Thursday, June 28, 2018

12:30 pm Registration

Aberration Detection

1:25 Chairperson’s Opening Remarks

David L. Hirschberg, PhD, Lecturer and Scientist, Department of Interdisciplinary Arts and Sciences and the Institute of Global Engagement, University of Washington, Tacoma

1:30 Technological and Scientific Gaps in Biosurveillance and BioDetection

Kris Scaboo, PhD, Co-Founder, Gate Scientific

2:00 BioWatch at Age 15: Maturing or Arrested Development?

Tom Slezak, PhD, Program Leader Informatics, Lawrence Livermore National Laboratory

Even within the Biodefense domain, many people are not very familiar with the BioWatch program: a nation-wide collection of aerosol collectors run 7x24x365 and tested daily for evidence of a wide-area bio-aerosol attack. As the nation’s bio-disaster early-warning insurance policy, it involves collaboration between DHS, the CDC, and state and local public health agencies. LLNL has been involved in developing, maintaining, and enhancing multiple aspects of both BioWatch (launched in early 2003) and its predecessor system, BASIS (2000-2003). The talk will provide insider historical context and discuss some of the technical, social, and political challenges BioWatch faces today.

2:20 Coastal Viral Communities and the Human and Ecosystem Implications

Shawn Polson, PhD, Director, Bioinformatics Core Facility, Center for Bioinformatics and Computational Biology; Director, Bioinformatics Network of Deleware, Deleware INBRE; Associate Professor, Department of Computer & Information Sciences and Department of Biological Sciences, University of Delaware

Research exploring ocean and human interactions is advancing our understanding of anthropogenic influences and disease-causing organisms in coastal ecosystems, which are potential threats to the long-term sustainability of the system. With approximately 40% of the world’s population estimated to be residing within 100 km of the coast, identifying the impact humans have on these natural habitats as well as the role that the coasts play in human wellbeing is of great importance.

2:40 Early Notification through Electronic Disease Surveillance

Wayne Loschen, Software Engineer, Johns Hopkins University Applied Physics Laboratory

This presentation will discuss the capabilities of ESSENCE, how it has evolved to be the civilian (CDC) and military (DoD) national syndromic surveillance system, and future directions to include advanced visualization, analytics, and predictive capabilities.

3:00 Technological and Scientific Gaps in Biosurveillance and BioDetection

David Hodge, PhD, Program Manager, Chemical Biological Defense Division, U.S. Department of Homeland Security

3:30 Refreshment Break in Exhibit Hall with Poster Viewing

Tools and Technology at the Point-of-Care

4:15 PANEL DISCUSSION: Impact of Diagnostic POC Technology

Moderator: Joany Jackman, PhD, Senior Scientist, Johns Hopkins University Applied Physics Laboratory

Panelists: Kris Scaboo, PhD, Co-Founder, Gate Scientific

Kent Lewandrowski, PhD, Director of Clinical Laboratories, Pathology, Massachusetts General Hospital

William Clarke, PhD, Director, Clinical Toxicology, The Johns Hopkins Hospital

Point-of-care (POC) technology is a game changing development in the field of medicine. It is potentially disruptive technology in that it has the potential to change the way that care is delivered to patients and in the way that clinicians and patients interact. In this panel we will discuss the impact of POCT, how should it be determined, what benefits are yet to be realized and what other impacts need to be evaluated. Please join the panel of experts to discuss the application of POCT and the metrics used to determine its value.

5:15 End of Day and Dinner Short Course Registration

6:00 Dinner Short Courses*

*Separate registration required

Friday, June 29, 2018

8:00 am Morning Coffee

Risk Anticipation

8:25 Chairperson’s Remarks

Luther Lindler, PhD, Senior Scientist (ST), Biological Programs, Chemical and Biological Defense Division Science and Technology Directorate, US Department of Homeland Security

8:30 KEYNOTE PRESENTATION: Applying Strategy and Analysis to the Biodefense Enterprise

Susan Coller Monarez, PhD, Deputy Assistant Secretary for Strategy and Analysis, Office of Strategy, Policy, and Plans, US Department of Homeland Security

This presentation will focus on the strategic environment (threat actors, emerging infectious diseases, budget constraints, complex mission ownership across the FSLTT enterprise, etc.) and how the USG needs to improve strategic planning, management oversight, accountability, and transparency to take meaningful steps in addressing the global biorisks.

9:00 KEYNOTE PRESENTATION: The Next Generation of Deployable Biodefense Capabilities for the Warfighter

C. Nicole Rosenzweig, PhD, BioSciences Division Chief, Edgewood Chemical Biological Center, US Army

The Department of Defense has fielded very few substantively improved biodetection capabilities over the past decade. Major improvements for fielded technologies depend heavily on commercial and academic technology breakthroughs. With the explosion of DIY synthetic biology as well as the miniaturization of mass spectrometers, Edgewood Chemical Biological Center is now developing a new generation of biodetection capabilities: synthetic biology to create ruggedized reagents capable of performing rapid, complex, and cheap detection; phage for tailored biodefense applications; mass spectrometers to identify toxins in the environment. This talk will highlight the tide of new biodetection capabilities and the importance of leveraging the development occurring in the academic and industrial sectors.

9:30 Biodefense to Support the Homeland Security Enterprise

Luther Lindler, PhD, Senior Scientist (ST), Biological Programs, Chemical and Biological Defense Division Science and Technology Directorate, US Department of Homeland Security

The Department of Homeland Security (DHS) Science and Technology Directorate (S&T) Chemical and Biological Defense Division (CBD) performs research and development for DHS and the Homeland Security Enterprise. Detection and surveillance research includes the Sensenet project and wearable sensors for monitoring human physiology. S&T CBD is also investing in a test beds in specific locations as a proving ground for current and future detection technologies. Finally, S&T has contributed to the response and recovery area by performing clean up and modeling testing for underground transportation. All of these programs will be discussed in the presentation to introduce the audience to the critical mission DHS S&T performs within the area of biodefense.

10:00 Networking Coffee Break

Threat Identification & Characterization

10:30 Redefining the Term and Approach to Bioterrorism: Emerging and Re-emerging Infectious Diseases

Jeffrey Stiefel, PhD, Executive Coordinator, Climate Change and Health Resilience, US Department of Homeland Security

11:00 Web Based Visual Analytics for Infectious Disease Surveillance

Alina Deshpande, PhD, Group Leader, Biosecurity and Public Health, Bioscience Division, Los Alamos National Laboratory

Situational awareness is important for both early warning and early detection of an infectious disease outbreak, and analytics that furnish information on how an infectious disease would emerge, re-emerge or spread provide enhanced situational awareness for decision makers/analysts/public health officials, and support planning for prevention or mitigation. In this presentation, I will describe two analytics developed at Los Alamos National Laboratory (LANL) that provide actionable information at varying spatial and temporal scales. Analytics for Investigation of Diseases Outbreaks (AIDO) can be used during investigations of unfolding infectious disease outbreaks.

11:30 Applications for Next-Generation Sequencing in Public Health

Martina Siwek, PhD, Program Manager, Health Surveillance, National Health Mission Area, Johns Hopkins University – Applied Physics Lab

This talk will discuss how JHU APL is leveraging our expertise in the areas of next-generation sequencing and public health practice to develop methods and insights into applying genomic information to augment and enhance public health awareness and response.

12:00 pm Luncheon Presentation (Sponsorship Opportunity Available) or Enjoy Lunch on Your Own

1:40 Chairperson’s Remarks

C. Nicole Rosenzweig, PhD, BioSciences Division Chief, Edgewood Chemical Biological Center, US Army

1:45 Development of Portable and Wearable Platforms to Detect Threats and Measure Human Performance in Resource Limited Environments

David L. Hirschberg, PhD, Lecturer and Scientist, Department of Interdisciplinary Arts and Sciences and the Institute of Global Engagement, University of Washington, Tacoma

2:15 Biosurveillance of Infectious Diseases at US Ports of Entry

Alena James, Chemical & Biological Defense ORISE Fellow, DHS Science and Technology Directorate

With more than one million travelers processed for entry into the United States on a daily basis, the integration of biosurveillance methods and detection technologies enables The Department of Homeland Security (DHS) to protect the US against new and emerging diseases that would otherwise compromise the nation’s public health security. This presentation will shed light on the current biosurveillance technologies and methods used to strengthen US border security and discuss the needs for new and updated technologies to improve infectious disease surveillance quality.

2:45 Networking Refreshment Break

Information Integration, Analysis & Sharing

3:00 Agro-Defense - A Holistic, All of Enterprise Approach

Kimothy Smith, PhD, Vice President and Chief Science Officer, ExcitePCR, Inc.

The ability to protect our agricultural industries, food supply, and public health sectors from natural introductions of biological agents, agro-terror threats, and emerging and re-emerging diseases is heavily dependent on an organized, strategic, and well-funded approach. This approach should institutionalize the “One Health” concept, be highly collaborative in nature, leverage all available resources and encompass an international, global health component. The One Health concept must be understood, adopted and become part of the fabric of the way in which we approach biodefense.

3:30 Bacterial Plant Disease Management Using Bacteriophages

Spela Alic, Department of Biotechnology and Systems Biology, National Institute of Biology, Slovenia

4:00 Close of Conference